With Many Hopes Pinned to Her Shoulders, Bertagnolli Finally Assumes NIH’s Top Post

A long-overdue example of a successful woman in biomedical research. A force for equity in clinical trials. A beacon to restore public trust in science. A defender of the “broken” health care system who enables the “greed” of the pharmaceutical industry.

As Monica Bertagnolli, M.D., settles in as leader of NIH—following what was less a rocky road and more a slow path with one huge boulder—she bears the hopes of many and the derision of few, most notably Sen. Bernie Sanders, I-Vt. For months, Sanders refused to hold a hearing on her nomination before the Health, Education, Labor and Pensions (HELP) Committee he chairs, ultimately relenting in October.[1]

On Nov. 7, the full Senate confirmed Bertagnolli’s appointment, and she began work as NIH’s 17th director two days later. Bertagnolli is the first surgeon and second woman to hold the post left vacant by former NIH Director Francis Collins nearly two years ago. She served as director of the National Cancer Institute (NCI) for a little over a year. President Joe Biden nominated her to lead NIH in May.

Sanders, who also voted “no” following the HELP hearing, and Sen. John Fetterman, D-Pa., were the only two Democrats to vote against her. Thirteen Republicans joined the Democratic majority. The vote was 62 to 36.

Among those with high hopes for Bertagnolli’s tenure is Sen. Patty Murray, D-Wash., who left as chair of HELP at the start of the current session of Congress to lead the chamber’s appropriations committee. Prior to the vote, Murray spoke passionately about both NIH generally and specifically praised Bertagnolli, noting the significance of her appointment and the promise it holds.

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